DHT is the primary androgen in the prostate. Dutasteride is a competitive inhibitor of both type-1 and type-2 isoenzymes of DHT, with 45-fold greater potency than finasteride against type-1 and type-2 isoenzymes. The remaining DHT is hypothesized to be from type-1 5-alpha-reductase. It is a primary factor in the development and progression of benign prostatic hyperplasia (BPH) and other prostate diseases and is also a major cause of hair loss. Since 2014 Alvi Armani has also offered a second topical solution with Dutasteride. M.D., F.A.A.D., is Clinical Professor of Dermatology at the College of Physicians and Surgeons of Columbia University in New York. It comes with side effects for men but they are rare. It’s important to note that the FDA has not approved Dutasteride for the treatment of hair loss but Glaxo has completed Phase 2 trials for its use in treating hair loss. 38 year old male from Madrid, Spain. Top. Dutasteride is not approved by FDA for hair loss but it is available as ‘off-label’ hair loss treatment for men at a dose of 0.5mg. This stuff is supposed to block between 92-100% of dihydrotestosterone conversion on 2.5mg / day and this level is reached after 2 weeks of using dutasteride. It is a primary factor in the development and progression of benign prostatic hyperplasia (BPH) and other prostate diseases and is also a major cause of hair loss. Dutasteride in its raw form is a white-yellowish powder. Impact of Hair Loss Forum. Board index Hair Loss Forums Women's Hair Loss Discussions; Dutasteride - female PMS study. Dutasteride 0.5mg/day decreases serum DHT 91% and scalp DHT 54%. However, Dutasteride is approved for hair loss in South Korea after clinical trials on Korean population. The patient had 4072 FU's placed into lateral slits in the front 1/3 of his head. Finasteride 5mg/day decreases serum DHT 71% and scalp DHT 38%. the side effects of both are very severe, and the risk is simply stupidly high, no matter how many silly and fake reports the pharmacuticals try to make about it not having that many side effects and great results. Both treatments work by inhibiting 5AR, the enzyme responsible for converting testosterone to dihydrotestosterone (DHT). However, since the Type I form of the 5 alpha-reductase that dutasteride blocks is not present in significant quantities in the hair follicle, these effects may not be as significant as one might expect. Only Finasteride Is FDA-Approved to Treat Hair Loss in Men. I was born in 1972 and first noticed a little hairline recession just after I turned 19 (in 19 At the time I said on the forum that when I do try I will update everyone after 6 months to let everyone know if it had any affect on me or not. Finasteride is a competitive inhibitor of 5-alpha-reductase that selectively inhibits the type-2 isoenzyme. Well I asked my doctor for Avodart and he said no. When I used it, I noticed faster than normal hair growth within a few weeks - be careful though, the sides take a long time to go away due to an insanely long half life. It is also approved in US, Japan and is … A safe haven for hair loss sufferers to discuss how balding affected them and hopefully find solutions. Studies have shown that 0.5mg of Dutasteride is an effective treatment for pattern baldness. He has developed a unique lateral slit technique, which provides improved naturalness and coverage in hair transplants. Topical Dutasteride. Dutasteride is a more powerful DHT inhibitor in that it prevents two enzymes, 5 alpha reductase type 1 and type II (finasteride blocks only type II) from converting testosterone into dihydrotestosterone, the primary hormone that causes male patterned hair loss. Hair Loss Forum © 2014. One of “America’s Top Doctors,” by Castle Connolly Medical and New York Magazine's "The Best Doctors in New York”. On the whole, dutasteride is for hair loss is a great tool. It should also be noted that balding older men who have taken Avodart to treat their enlarge prostates have sometimes noticed hair regrowth in areas of their scalps that have been totally barren for many decades. On hair loss forums, Avodart/Dutasteride related testimonials are either not broken out in a separate subcategory, or not updated regularly. The main negative factor mentioned in such reviews is obviously the fear of side effects, though the immediate effects do not seem to be any more worrying than those from the use of … from the looks of it, dutasteride vs finasteride is a lost battle already - especially in hair loss and helping those kind of conditions. Update: Yesterday (June 4th, 2018), Ashton Kutcher appeared on Conan and discussed his past 10-year usage of Avodart (Dutasteride) to maintain his hair, prior to quitting several years ago. All Rights Reserved. Excerpt: I can get a cheap source of dutasteride from India. Dutasteride is approved by the FDA, but only as a treatment for BPH. The results of the study showed that dutasteride increased hair counts in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride 5mg at 12 and 24 weeks. By WomensHairLossProject in forum Women's Hair Loss Treatments, http://www.bernsteinmedical.com/reso...inasteride.php, Hair Transplant Videos, Patient Interviews and Surgeon Q & A, Hair Transplant Results By IAHRS Recommended Surgeons, Histogen's Hair Stimulating Complex (HSC), Techniques in Possible Donor Regeneration and Multiplication, Hair Replacement: Wigs, Toppers, Hair Integration, Know the Facts About Hair Transplant by Dr. Suneet Soni. Initial tests show that using dutasteride for hair loss is a very effective strategy. Hair Loss Forum » Early treatment of alopecia. Consumer reviews of dutasteride's effectiveness in treating hair loss can be found at online forums and seem largely positive. So… Skip to content. Any opinions on use of dutasteride as compared to finesteride (propecia) for treatment of hair loss? Hopefully it won't give me any side effects if I take it. Anyway, before I start my TRT protocol again, I'd like to hear if anyone has experience taking "micro doses" of Dutasteride to control DHT levels, and thus prevent acne and hair loss. 1 post • Page 1 of 1. Dutasteride is not FDA approved for women. Approximately 85% to 90% of DHT is suppressed by the inhibition of type-2 isozymes. You may have heard some people talking about their great results with Avodart, which probably is true. Dutasteride and finasteride are both 5-alpha-reductase (5AR) inhibitors. So I guess I'll just have to deal with going bald. It also has a lot of other uses, which is why it’s a popular type of antiandrogen. (Dutasteride is most commonly prescribed to treat an enlarged prostate, but other 5-ARIs have been used to treat hair loss. Dutasteride is a medication that is often used to help treat prostate problems in men. It has slowed down the 'hair loss process' but with its limitations. Avodart (Dutasteride 0.5mg) is an FDA approved medicine for the treatment of Benign Prostatic Enlargement or BPH also known as prostate enlargement. I've been taking Propecia since about 2001 (or 2002). Dr. Victor Hasson graduated with honors from the University of Cape Town, South Africa in 1984. If you are using Dutasteride or Avodart as a treatment for thinning hair or hair loss otherwise known as Male Pattern baldness, we recommend that you also consult these other resources for more hair loss and hair … Is Dutasteride More Effective Than Finasteride For Stopping Hair Loss In short, yes on paper dutasteride is the most effective medication on the market for stopping hair loss. Moderator: moderators. Patient had several unsuccesful plug hairtransplants and mini/microgratfts. However, it is important to remember that dutasteride has not been FDA-approved to treat androgenic alopecia (genetic hair loss). Is currently practicing full time in Vancouver, BC, Canada. Dedicated to discussions and support for women suffering from hair loss. Thanks Spencer. I can just barely hide my thinning spots now. I know that Dutasteride is known to CRUSH your DHT levels, and I definitely don't want to do that because I know DHT is important for well-being and for sex drive, among other things. Tricia Prolific Poster Posts: 325 Joined: Thu Jun 03, 2004 1:19 pm Hair Loss: Propecia vs Dutasteride/Avodart? Dutasteride is a competitive inhibitor of both type-1 and type-2 isoenzymes of DHT, with 45-fold greater potency than finasteride against type-1 and type-2 isoenzymes. According to Rittmaster, men born with the type I 5-alpha reductase enzyme but without the type II 5-alpha reductase enzyme (the kind DHT blocks) experience hair loss when given Testosterone injections. I'll have to ask my doctor next time I go if he can give me a prescription for Avodart. 1 . HAIR LOSS RESOURCES. Dutasteride is known to have a much more powerful 5-alpha reductase inhibitor than the leading hair loss treatment Propecia, or Finasteride. Currently, Avodart is not an approved medicine for the treatment of male pattern hair loss. My hair loss has gotten a lot worse lately. Please join this discussion about hair loss [dutasteride (anti dihydro test) + test] within the Anabolic Steroids category. Dutasteride for Female Hair Loss: Top 10 things to know . Propecia only inhibits type 2 and 3 of the enzyme while Avodart reduces the effects of type 1 as well. I've been using Topic to style my hair, but with the (slow) hair loss continuation, I don't know for how much longer Topic can still camouflage the areas with less hair. Re: Dutasteride (anti-Hair loss drug) I have used it, and it is indeed more effective than finasteride at preventing hair loss. Hi,I used to visit this site and forum multiple times daily back in the early 2000s and was almost completely pre-occupied with the fear of my hair falling out. That doesn’t it can’t be used for women it just means that it was formally approved for another use. I may give this a try, since Propecia/Proscar didn't help me. However, please note that effectiveness of Dutasteride or Avodart as a hair … It is insoluble in water but can easily be dissolved in ethanol (44mg/mL), methanol (64 mg/mL) and polyethylene glycol 400 (3mg/mL). The dual inhibition resulting from dutasteride treatment may be beneficial for treat male pattern baldness better than Finasteride . In the study, 416 men with male pattern hair loss (MPHL) ages 21 to 45 years old, were randomized to receive dutasteride 0.05, 0.1, 0.5 or 2.5 mg, finasteride 5 mg, or placebo daily for 24 weeks. Dutasteride, the medication discussed in this article, blocks both types of the enzyme and so it is believed it will be more effective at treating hair loss. Opt for the best human hair toupee to cover your baldness. Although dutasteride is approved as a treatment for male pattern baldness in some countries, it hasn’t received FDA approval as a hair loss drug in the United States. Based on these results, dutasteride should be significantly more effective in the treatment of androgenetic alopecia than finasteride. Dutasteride is a prescription drug that’s taken as a capsule. If you still fear the medication unwanted effects, try a hair replacement system. So far I can't say much about dutasteride but it probably reduced my hair loss a bit more than finasteride, no sides yet after 2 months. It belongs to a group of drugs called 5-alpha-reductase inhibitors (5-ARIs). Johnson wrote: ↑ 2 years ago I remember asking a ton of questions back in February about Dutasteride and some of the answers were unclear and the consensus was that everyone responds differently so just give it a go. The following are my professional opinions and recommendations about the use of dutasteride for treating hair loss in women. The increased efficacy of Dutasteride is felt to b… Sexual side-effects appear to be slightly less in dutasteride, although dutasteride appears to remain in your system up … We take a closer look at Dutasteride and how it can be beneficial for various problems, including hair loss. I first published this post on February 26, 2018, but am now updating and republishing it because of an important development. 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